Director, Clinical Operations

Pharma Medica Research (PMRI) Inc. is a Contract Research Organization that strives for innovation and original solutions in a highly regulated and competitive industry. If your career goals align with innovation and original thinking you will be the perfect candidate to be part of an inclusive, adaptable, and forward-thinking organization. Our reputation for delivering high quality research is outstanding. At PMRI we are committed to making a difference in healthcare and people’s lives. Come join our team!

We are currently searching for a Director, Clinical Operations to join our Toronto Team!

Duties and Responsibilities:

• Oversee daily operations of the clinic facility and coordinate clinic scheduling with project managers.
• Review study protocols for operational feasibility and subject safety.
• Plan and manage complex study designs, ensuring timely preparation, supply availability, and operational readiness. Oversee study start-up activities, site activation processes, and drug management to support seamless clinical trial execution.
• Ensure all clinical equipment is properly calibrated and fully prepared for study use.
• Facilitate collaboration across clinical departments and with other teams to streamline procedures and communication.
• Monitor clinic procedures to ensure quality and data integrity; implement corrective and preventive actions.
• Assist in clinical software testing, training, and deployment.
• Review and approve deviations, audit reports, and corrective actions.
• Oversee multiple clinic departments, with department managers reporting directly to this role
• Execute Phase I clinical trials in compliance with GCP, ICH, FDA, and Health Canada regulations.
• Enforce documentation standards and oversee study logistics.
• Develop, revise, and ensure training in clinic SOPs.
• Identify and qualify vendors for specialized procedures; Assist in clinical supply chain and vendor communications.
• Oversee and assist recruiting manager in recruitment and screening activities and volunteer compensation arrangement.
• Timesheet approvals
• Collaborate with Human Resources to address and resolve critical clinic staff matters.
• Recruit, onboard, and mentor clinical staff; conduct performance reviews and support development.
• Provide strategic input into clinical development programs and maintain inspection readiness.
• Identify operational risks and develop mitigation strategies.
• Drive innovation and continuous improvement in clinical operations
• Involved in cross-departmental collaboration to ensure timely and accurate delivery of study report

Qualifications

• MSc in Life Sciences or related field; CCRP Certification preferred.
• Minimum 8–10 years of management experience in clinical research (preferably in a CRO setting).
• At least 5 years in a leadership role.
• Strong knowledge of GCP, ICH, FDA, and Health Canada regulations.
• Proven ability in strategic planning, team leadership, and cross-departmental communication.
• Excellent interpersonal and communication skills.
• Strong computer skills in Microsoft Office Applications

We offer:

• Competitive compensation plan
• Mentorship Opportunities
• A benefit plan that is fully paid for by PMRI, including healthcare, dentalcare, vision care, LTD, Life Insurance, AD&D, along with a Health Spending and Wellness Spending Accounts and a voluntary RRSP Contribution Plan
• Opportunities for advancement and career progression
• A generous Employee Milestones Awards Program
• Corporate Discounts Program
• Learning Support Programs
• Friendly atmosphere, culture of learning

Please note all applications must be eligible to work within Canada.

PMRI is an Equal Opportunity Employer; promoting accessibility and inclusivity at work and offering accommodation for applicants as required and requested.

We thank all applicants for their interest; however, only those selected to proceed in the interview process will be contacted.